CAS number: 124-04-9
Chemical Formula: C6H10O4
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Adipic acid or Hexanedioic acid is the organic compound with the formula (CH2)4(COOH)2. Adipic acid otherwise rarely occurs in nature, but it is known as manufactured E number food additive E355. Adipic acid has been incorporated into controlled-release formulation matrix tablets to obtain pH-independent release for both weakly basic and weakly acidic drugs. significant amounts of adipic acid are used as a food ingredient as a flavorant and gelling aid.
Adipic Acid USP NF Grade
1,4-Butanedicarboxylic acid [CAS Number 124-04-9].
Adipic Acid contains not less than 99.0 percent and not more than 101.0 percent of C6H10O4, calculated on the dried basis.
Adipic Acid FCC Food Grade
Hexanedioic Acid; 1,4-Butanedicarboxylic Acid
Adipic Acid occurs as white crystals or a crystalline powder. It is not hygroscopic. It is freely soluble in alcohol, soluble in acetone, and slightly soluble in water.
Function: Buffer; neutralizing agent.
Assay: Not less than 99.6% and not more than 101.0% of C6H10O4, calculated on the anhydrous basis.
Lead: Not more than 2 mg/kg.
Melting Range: Between 151.5° and 154°.
Residue on Ignition: Not more than 0.002%.
Water: Not more than 0.2%.
Adipic Acid BP Grade
CAS Number: 124-04-9
Action and use: Excipient.
Content: 99.0 per cent to 101.0 per cent (dried substance).
Appearance: White or almost white, crystalline powder.
Solubility: Sparingly soluble in water, soluble in boiling water, freely soluble in alcohol and in methanol, soluble in acetone.
A. Melting point: 151C to 154C.
B. Infrared absorption spectrophotometry.
Solution S: Dissolve 5.0 g with heating in distilled water and dilute to 50 ml with the same solvent. Allow to cool and to crystallize. Filter through a sintered-glass filter (40). Wash the filter with distilled water. Collect the filtrate and the washings until a volume of 50 ml is obtained.
Appearance of solution: The solution is clear and colourless.
Dissolve 1.0 g in methanol R and dilute to 20 ml with the same solvent.
Related substances: Liquid chromatography To pass the test.
Chlorides: Maximum 200 ppm.
Nitrates: Maximum 30 ppm.
Sulphates: Maximum 500 ppm.
Iron: Maximum 10 ppm.
Heavy metals: Maximum 10 ppm.
Loss on drying: Maximum 0.2 per cent, determined on 1.000 g by drying in an oven at 105C.
Sulphated ash: Maximum 0.1 per cent.
Dissolve 60.0 mg in 50 ml of water. Add 0.2 ml of PhPh solution and titrate with 0.1 M sodium hydroxide. 1 ml of 0.1 M sodium hydroxide is equivalent to 7.31 mg of C6H10O4.
A. R = CH2-CO2H: pentanedioic acid (glutaric acid),
B. R = CO2H: butanedioic acid (succinic acid),
C. R = [CH2]3-CO2H: heptanedioic acid (pimelic acid).
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